ACTH - Adrenocorticotropic Hormone

Test Sample Type

• Blood

Normal Values

• In a.m.: 25-100 pg/ml
• In p.m.: 0-50 pg/ml

Purpose of the Test

• To diagnose Cushing's disease
• To differentiate primary and secondary adrenal insufficiency

Increase in

• Primary adrenal insufficiency
• Cushing's disease
• Congenital adrenal hyperplasia
• Ectopic ACTH syndrome

Decrease in

• Primary adrenal hypersecretion
• Cushing's Syndrome

Interfering Factor

• Noncompliance with medication, diet, or activity restrictions
• Administration of radioactive material within 7 days
• Pregnancy
• Ingestion of Alcohol
• Amphetamines
• Calcium gluconate
• Corticosteroids
• Estrogen
• Lithium
• Spironolactone